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In vivo rodent longevity models have examined the compound's influence on tissue-specific telomere length dynamics across serial sampling timepoints

GCV reduced Doxorubicin-induced p16-RLUC expression (Fig

Clin Cancer Res 11(19 Pt 1):6916-6923, 2005

Unexpectedly, we observed a biphasic effect: early sensitization to ferroptosis induced by glutathione depletion was subsequently counteracted by a marked increase in ferroptosis resistance